Taking herbs and blood pressure medications may cause reflux esophagitis. Reflux esophagitis refers to damage to the esophagus caused by the reflux of digestive juices into the esophagus for various reasons. Reflux esophagitis can be caused by abnormal functioning of the muscles at the junction of the esophagus and the stomach that control the prevention of reflux of gastric contents, weakening of peristalsis in the esophagus, loss of the ability of the esophagus to resist various types of injuries from a variety of causes, oversensitivity of the esophagus to a variety of stimuli, and impairment of the stomach’s ability to expel food. Prolonged application of antihypertensive drugs or herbs may cause abnormal function of the muscles at the junction of the esophagus and the stomach, thus causing the disease. Gastrointestinal imaging or gastroscopy can be used for differential diagnosis when epigastric pain, discomfort, acid reflux, and heartburn occur during the patient’s use of medication. These patients are recommended to lie down with the head of the bed elevated, do not lie down immediately after meals, no smoking, no alcohol, do not eat spicy and stimulating food.