Mr. Zhang, a 50-year-old man, had been plagued by sudden onset of chest tightness at night for a long time, and had to sit up from bed during numerous episodes of sudden onset of breathlessness at night. After ECG, cardiac enzyme profile, coronary angiography and chest CT examination all found no obvious abnormalities, and repeatedly ran around for treatment with poor results. 2 weeks ago the symptoms recurred and Mr. Li came to the First Affiliated Hospital of Henan University with a feeling of trying. He was seen by Dr. Dong Yanjun at the Thoracic and Cardiovascular Surgery Clinic. After listening to Mr. Zhang’s medical history for many years, Dr. Dong found that most of Mr. Zhang’s sudden respiratory distress occurred in the evening when he was sleeping after a full meal, and immediately performed a barium meal imaging of the gastrointestinal tract. After laparoscopic “esophageal hiatus hernia repair + anti-reflux surgery” treatment, Mr. Zhang is now discharged from the hospital. Gastroesophageal reflux disease is a disease in which stomach contents flow back into the esophagus, causing symptoms and complications such as heartburn, acid reflux and chest pain. Some patients may present with asthma, cough, and chest pain, which can easily be misdiagnosed as asthma, chronic bronchitis, or even coronary artery disease. Patients may be seen in multiple disciplines such as respiratory medicine, cardiology, otorhinolaryngology, and dentistry. Severe and prolonged disease can lead to reflux esophagitis, esophageal ulcer, esophageal stricture, Barret’s esophagus and Barret’s esophagus cancer. Gastroesophageal reflux disease is mainly due to relaxation of the lower esophageal sphincter. The relaxation of the lower esophageal sphincter can cause reflux of gastric contents into the esophagus, pharynx and trachea, resulting in various adverse symptoms. Gastroesophageal reflux disease is most common in the middle-aged and elderly population. In recent years, there is a trend of younger age, which is related to poor lifestyle habits such as excessive obesity, long-term consumption of carbonated beverages, smoking, alcohol consumption, and full dinners. Previous medical treatment is mainly based on acid suppression therapy to neutralize gastric acid and reduce the damage to the esophageal mucosa. Adjunctive application of gastric motility drugs promotes gastric emptying, so that reflux can be reduced. However, drug therapy can only reduce the damage caused by reflux, but not control reflux, which is only non-acid reflux at this time. And once the medication is discontinued, many patients will have recurrent symptoms that require doubling the medication to control. Minimally invasive technology is developing rapidly, and laparoscopic fundoplication is now the “gold standard” for the treatment of GERD, and if combined with an esophageal hiatal hernia, hernia repair surgery is performed at the same time. The procedure is performed by making only 4-5 small “keyhole” incisions of 0.5-1.0 cm in the patient’s abdomen, and the patient can eat and resume daily activities the day after surgery and be discharged from the hospital in three to five days.