Discomfort in the throat is commonly caused by acute pharyngitis, reflux pharyngitis, bronchitis, etc. First of all, it is necessary to make a clear diagnosis, and under the guidance of the doctor for the specific disease treatment. 1. Acute pharyngitis: throat discomfort occurs due to inflammation of the pharyngeal mucosa, submucosa and lymphatic tissues caused by bacterial and viral infections, which requires drinking more water and paying attention to rest. Compound borax gargle and warm saline gargle can be applied to help promote the dilution of secretions, which can be easily discharged. Dumiphene tablets and watermelon cream throat lozenges can also be used to improve symptoms. 2. Reflux pharyngitis: due to acid reflux caused by throat discomfort, need to eat less and more meals, can apply proton pump inhibitors, such as omeprazole, lansoprazole, etc. to reduce symptoms. 3. Bronchitis: e.g. Streptococcus pneumoniae infection caused by rain, cold and exertion, cough, sputum, pharyngeal discomfort, herpes of the oral cavity and buccal mucosa, etc. Antibiotics, e.g. penicillin, etc., need to be applied to treat the symptoms. When throat discomfort occurs, consult a doctor in time to find out the cause, and standardize the medication and treatment under the doctor’s guidance.