There is no such thing as “the most effective way” to get rid of age spots. The occurrence of age spots is related to natural aging and other factors, and the treatment methods for age spots include medication, surgery, laser treatment, etc. Doctors will choose the treatment methods according to the specific conditions of patients. Age spot is a kind of degenerative skin change of the elderly, which refers to the appearance of brown spots ranging from rice grains to nail cap size on the exposed parts of the face and back of the hands, with clear boundaries, seborrheic scabs on part of the surface, and hyperkeratosis. Age spots are related to natural aging, sunlight damage, heredity and other factors. 1. Drug treatment: Drugs can lighten age spots to a certain extent, related drugs include vitamin E, vitamin C, glutathione, vitamin A cream and so on. 2. Surgical treatment: if age spots are suspected to be malignant, they should be removed through surgery in time and pathologic examination should be done. 3. Laser treatment: laser can destroy the diseased tissues without affecting the normal tissue structure, so as to achieve the purpose of removing age spots. In daily life, patients should strengthen the management of skin, keep the skin clean, avoid excessive sunshine and keep a happy mood. Patients should follow the doctor’s prescription for treatment, do not self-medication, so as not to cause adverse reactions.