The uneven skin color of the face may be related to the white chaff rash, vitiligo, ringworm, etc., need to carry out drug treatment, surgical treatment, physical therapy, etc.. 1. white chaffeas: this disease is self-limiting, generally do not need treatment, can follow the doctor’s prescription of 5% urea ointment and other moisturizing cream, hydrocortisone ointment and other glucocorticosteroids. 2. Vitiligo: can follow the doctor’s prescription topical fluticasone propionate and other glucocorticoid ointment, pimecrolimus and other calcium-modulated neural phosphatase inhibitors. If necessary, the feasible surgery will be autologous tissue or melanocyte transplantation to the depigmented area; light therapy and other physical therapy is conducive to restoring the skin color of the white spots. 3. ringworm: can follow the doctor’s instructions external naftifine ketoconazole cream and other antifungal drugs, if necessary, oral antifungal drugs itraconazole. It is recommended that people with uneven skin color go to the hospital in time to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.