When bronchial obstruction occurs in late stage of lung cancer, it can be treated by local resection, radiotherapy, chemotherapy and symptomatic treatment. Lung cancer is a malignant tumor caused by smoking, heredity and other factors, with the development of the tumor, it can lead to bronchial obstruction, at this time, clinical manifestations such as dyspnea, coughing and sputum can appear. If there is a chance of surgery, local resection of tumor under bronchoscopy is feasible; radiotherapy, chemotherapy and targeted therapy are also available. Commonly used chemotherapeutic drugs include paclitaxel, gemcitabine, etc. Targeted drugs include gefitinib, etc., which should be applied under the guidance of doctors. In addition, implantation of bronchial stent, non-invasive ventilation and other methods of symptomatic treatment. Patients need to actively cooperate with doctors in order to obtain a better prognosis.