According to the survey, only 30% of cancer pain patients in China have their pain effectively relieved, and many cancer patients do not consider cancer pain treatment as a priority option in treatment, often enduring and carrying it by themselves, and directly using strong opioid drugs such as morphine when they can’t carry it anymore. Therefore, seeking ways to relieve pain is the common goal of health care professionals, patients and their families. Cancer pain patients “tolerate pain” brings many negative effects, and analgesic treatment can improve the efficacy of anti-cancer treatment. Faced with pain, many people hold the idea of “just bear it”. Others are reluctant to seek medical treatment for fear of affecting their work or bothering their relatives and friends. Through the observation of patients, we found that cancer pain not only makes patients suffer from pain all day long, but also causes the following negative effects: 1.It often leads to pain, poor quality of life, serious sleep disorder, loss of appetite and loss of confidence in treatment. 2.It leads to the decrease of immunity and disease resistance, which in a certain sense accelerates the development of tumor and causes a vicious circle. 3.Cancer pain affects coagulation function, and many patients will produce vascular vein thrombosis and life-threatening complications. 4. Severe cancer pain also affects cardiovascular function and respiratory function. Some patients with heart disease may have cardiovascular and cerebrovascular danger because of pain. 5. Chronic severe pain not relieved for a long time will develop into intractable cancer pain and become a disease in real sense. In addition, the unbearable pain will cause patients to have severe anxiety or heavy depression. ”Many people think that pain treatment is only ‘treating symptoms’, which can only improve the symptoms and has little significance; anti-tumor treatment is the ‘cure’,” Fan Bifa said. “This view is unscientific. Cancer pain control is one of the four key items of cancer control. It is because by getting pain under control, the patient’s state is likely to be more conducive to tumor treatment.” In 2010 the Massachusetts General Hospital Oncology Center found through research that aggressive analgesia while treating tumors enhances anti-cancer outcomes. Researchers randomized newly diagnosed patients with advanced metastatic non-small cell lung cancer into two groups: one group received antitumor therapy combined with early palliative care aimed at analgesia, and the other group received only antitumor therapy. The survival and quality of life indicators of the two groups were observed at 12 weeks after treatment. The results showed that patients in the analgesic group not only had a significantly higher quality of life than the antineoplastic group alone, the proportion of patients who experienced depression was significantly lower, and the average survival time was significantly longer. Opioids can avoid addiction under the guidance of doctors, and the use of dulcolax in cancer pain treatment is prohibited. Some patients resist pain treatment partly because they fear drug addiction. Fan Bifa explains that addiction can be avoided under the guidance of a doctor, “Drug addiction is a chronic, relapsing, compulsive behavior in which patients continue to take medication regardless of the consequences, and is divided into two categories: physical dependence and mental dependence. In addiction, the patient seeks not somatic pain relief, but mostly psychological satisfaction, i.e. ‘euphoria’, and this condition is called ‘addiction’. Therefore, the use of such drugs under the guidance of a specialist, the doctor will carefully select the drug according to the patient’s pain situation, according to the need to determine the dose, the effect of the drug is only to act on the pain, to avoid drug addiction to the maximum extent.” According to the introduction, in general, anti-inflammatory and analgesic drugs are not addictive; medium-strength analgesics do not produce addiction under regular use; opioids, including morphine, aminophen ucodone, dulcolax, etc., they have a certain degree of addiction, the condition requires, regular use can avoid addiction. In addition, Fan Bifa added that the opioid with the greatest possibility of addiction is dulcolax, and in the treatment of cancer pain, it is generally not used for routine cancer pain treatment because of its addictive nature and toxic effects on the central nervous system. As early as 1996, the Ministry of Health explicitly prohibited the use of dulcolax in cancer pain treatment. As for morphine and other drugs, they are the most commonly used drugs in clinical treatment of various intractable pains. It has little side effects and good pain relief effect, and will not cause addiction as long as the treatment method is regulated and the dosage is well grasped.