The question was modified to read: Is total cholesterol 6.3mmol/L serious and do I need to take medication? Total cholesterol 6.3mmol/L is significantly elevated and seriously jeopardizes human health, and medication is recommended for treatment. The normal range of serum total cholesterol is 2.85-5.69mmol/L, which is the sum of cholesterol contained in all lipoproteins in the blood, including free cholesterol and cholesteryl esters. Elevated total cholesterol is diagnosed as hypercholesterolemia, which is a high risk factor for atherosclerosis and coronary heart disease. For patients with hypercholesterolemia, it is recommended to actively use statins for cholesterol-lowering, such as simvastatin, resuvastatin, and atorvastatin. Statins can lower serum cholesterol concentration by competitively inhibiting endogenous cholesterol synthesis rate-limiting enzyme activity. Specific medications should be prescribed by a physician. Statins may have hepatotoxicity and nephrotoxicity, so please follow the doctor’s instructions, and regularly review the liver and kidney functions. Not recommended for patients with active liver disease, allergy to drugs, pregnant and lactating women.