The duration of medication for nodular goiter, 1 to 2 years after surgery is the optimal duration of medication, and unnecessarily prolonging the duration of medication increases medical costs and does not reduce the postoperative recurrence rate. The duration of postoperative medication for thyroid cancer, on the other hand, is lifelong. The biggest inconvenience of taking thyroxine is that you need to check your thyroid function regularly, especially during the first 3 to 6 months of taking the medication, and you need to visit your treating doctor frequently, sometimes once every 15 to 20 days, to adjust the optimal dose of the medication. The patient will gradually adapt as the time and dosage are adjusted.