High differential pressure in the elderly may be due to physiological factors, such as aging, and can be improved by lifestyle and medication. It may also be due to pathological reasons, such as anemia, vascular sclerosis or heart valve disease, etc. Different treatment methods are available for different reasons, and generally, allopathic treatment, medication and surgical treatment are used. 1. Physiological causes: As we age, the elasticity of blood vessels decreases, leading to a large pressure difference in blood pressure. At this time, it is necessary to control the intake of sodium and fat, eat more fresh fruits and vegetables, and take some medicines to adjust blood lipids and soften blood vessels under the guidance of doctors. 2. Pathological causes: anemia, vascular sclerosis or heart valve disease can lead to large differential pressure. (1) Anemia: Insufficient or reduced production of red blood cells, blood loss, etc. can lead to anemia, which is usually treated by treating the cause and finding the cause of anemia. (2) vascular sclerosis: vascular sclerosis is atherosclerosis, age increase, high fat blood, etc. can lead to atherosclerosis, generally through drug treatment, such as aspirin. (3) Heart valve disease: Heart valve disease is a heart disease caused by inflammation, mucus-like degeneration, degenerative changes, congenital malformations, ischemic necrosis, trauma and other causes of valve damage, resulting in stenosis or closure of the valve due to heart disease. Surgery is usually required. Large blood pressure differentials, after excluding physiological factors, should be promptly consulted to avoid delay.