HIV-positive patients who have normal immune function after regular treatment and have no other comorbidities can generally undergo mastopexy surgery. HIV positivity is not a contraindication to mastopexy surgery. If an HIV-positive patient is diagnosed with breast enlargement, he or she needs to voluntarily inform the doctor of the HIV infection, and the decision will be made by a medical professional after a thorough evaluation of the patient’s physical condition. In addition, not all hospitals are able to perform surgery on HIV-positive patients, and patients need to visit designated medical institutions for HIV-infected patients set by the CDC and the Health Planning Commission. HIV-positive patients should take the initiative to inform the doctor of their medical history when they visit the clinic, and should never hide their infection history, as this may lead to serious consequences.