Nasal congestion may be caused by oral administration of pentavalent rotavirus vaccine, which is an adverse reaction to the vaccine and usually resolves on its own or can be treated with medication. Oral administration of pentavalent rotavirus vaccine may cause common adverse vaccine reactions, such as fever, cough, nasal congestion, or redness, swelling and pain at the site of vaccination. Nasal congestion is less likely to occur, but may be triggered by the vaccine in some weak or sensitive people, and usually disappears within 2 to 3 days after vaccination. It is recommended that before vaccination, nutritional supplementation and body protection can be done to enhance their own immunity as much as possible to reduce the incidence of adverse reactions. For nasal congestion induced by oral administration of rotavirus pentavalent vaccine, if the symptoms continue to worsen or cannot be relieved on their own, nasal cleansing can be chosen to effectively remove the obstruction, which can ensure that the nasal passages are clear. After oral administration of pentavalent rotavirus vaccine, you can first observe for 24 to 72 hours to determine whether you have any symptoms of discomfort. If symptoms appear, you need to consult a doctor in time.