Most patients often mistake shingles for a skin condition and only remember to come to the pain unit for further treatment after a period of treatment in the dermatology department because of severe pain. The first sight of the patient always leaves us with a deep impression of severe pain causing painful expressions, fidgeting or forcing the patient into a position! The diagnosis can be clarified by the patient’s complaint, careful questioning of the medical history and treatment, herpes zoster-like changes in the affected skin that can be observed through physical examination, combined with the obvious tenderness of the lesioned skin, etc. Postherpetic neuralgia mainly has the following clinical features: 1. electroshock-like, knife-like or tearing-like episodes of pain (sometimes can be triggered by light friction such as normal clothing), with pain at night, and patients often have difficulty sleeping. Most patients with postherpetic neuralgia have intermittent episodes of pain, with a frequency of less than 10 episodes per minute and a duration of a few seconds to more than 10 seconds per episode, often accompanied by persistent pins and needles-like burning pain between episodes, which is relieved by cold and aggravated by heat; some patients have abnormal sensation in the lesion area; 3. Severe cases even have suicidal tendencies. We emphasize the word “early” in the diagnosis and treatment of PHN. We recommend that patients with shingles come to the pain clinic as soon as possible, within three months of the onset of pain. Common treatments include nerve root block therapy, pharmacotherapy, physical therapy and psychotherapy, etc.: 1. Only by accurately delivering the anti-inflammatory and analgesic solution to the damaged nerve roots can the nerve be repaired and the pain effectively controlled in the shortest possible time. 2, drug treatment as a supplement The common drugs used clinically to relieve acute postherpetic neuralgia are antidepressants, anticonvulsants, moderate and severe pain medications. In the recent stage, the new drug Pregabalin (Lerica) has made significant progress in controlling pain in PHN patients as the first-line clinical drug. 3. Combined physical therapy Our hospital introduced Japanese original super laser irradiation equipment, which is non-invasive and safe, together with nerve root block injection anti-inflammatory and pain relief solution technology, can rapidly control the intensity and frequency of pain attacks in PHN patients. 4.Psychotherapy intervention Psychotherapy occupies a considerable position in general pain outpatient treatment, and is even more important in the treatment process of PHN patients. Without systematic psychological assessment and treatment, it is very difficult to control postherpetic neuralgia satisfactorily in clinical practice. The technical cooperation between our pain clinic and the psychology department allows us to provide scientific psychological assessment and treatment to each PHN patient. In conclusion, postherpetic neuralgia is still a world-class problem, and the pain department of Ruijin Hospital Jiading North Hospital has developed a distinctive and effective treatment plan after repeated practice, which has relieved patients of their pain and helped them return to normal work and life!