Taking paroxetine no more pleasure may be caused by drug side effects, reduced sensitivity of the glans and prostatitis. 1. Drug side effects: paroxetine is an antidepressant, mainly for the treatment of various types of depression, obsessive-compulsive neurosis and other diseases. Some patients may experience side effects such as sexual dysfunction, diarrhea and weakness after taking it. 2. Decreased glans sensitivity: It is also possible that patients with low glans sensitivity may also experience the phenomenon of patients taking paroxetine without pleasure, as well as symptoms such as dull glans sensation, delayed ejaculation or a significant decrease in pleasure. 3. Prostatitis: prostatitis caused by pathogenic bacterial infection or certain non-infectious factors may lead to patients taking paroxetine without pleasure. Its typical symptoms are sexual dysfunction, localized pain and so on. When patients take paroxetine without pleasure phenomenon, it is recommended to go to the hospital in time to check, and according to the cause of treatment.