Ankle pain is often seen in ankle trauma and strain, degenerative diseases, rheumatoid arthritis and gouty arthritis, etc. According to the patient’s condition, general treatment, physical therapy, drug therapy and surgical treatment can be given. 1. Trauma and strain: trauma and strain history of ankle joints, patients need to pay attention to rest, avoid strenuous exercise, walking for a long time and weight bearing, etc., and local hot compresses can be given to relieve pain, and non-steroidal anti-inflammatory drugs, such as ibuprofen, can be given to treat the pain when it is obvious. 2. Degenerative lesions: mostly occurring in elderly patients, ankle joints have osteophytes, cartilage damage and joint wear and tear, part of the osteoarthritis can occur. It is also necessary for patients to reduce weight-bearing and strenuous exercise, the use of diclofenac sodium and other anti-inflammatory drugs, if necessary, can also be injected into the ankle joint sodium vitrate and other drugs. 3. Rheumatoid arthritis: belonging to autoimmune diseases, can also be given ibuprofen and other non-steroidal anti-inflammatory drugs, if necessary, can be given to prednisone and other glucocorticosteroid drugs. 4. Gouty arthritis: it is related to high uric acid, and colchicine and other drugs are given to treat it in the acute stage, and benzbromarone and other drugs to reduce uric acid can be given to treat it in the remission stage. Ankle pain caused by many diseases, including lumbar disc herniation and ankle tumors, etc. It is recommended that patients go to the hospital to improve the auxiliary examination, to clarify the cause of the disease, the drugs have certain side effects and contraindications, so it is necessary to use under the guidance of a professional physician.