Glutaminase and glutamate aminotransferase 100U/L can usually be lowered in 1-4 weeks, depending on the cause of the elevation. Transaminase is an important indicator of liver function test, usually refers to alanine aminotransferase and glutamate aminotransferase, the normal value is usually 10-40U / L, transaminase 100U / L, indicating liver cell damage caused by liver function abnormality, need to protect the liver and lower the enzyme and other treatments. Generally, it can be lowered in 1-4 weeks, but the time to lower the enzyme may vary depending on the cause of the elevated transaminases of liver damage. If the liver function is slightly impaired due to heavy drinking, tiredness, late night or strenuous exercise before the examination, and the transaminases are elevated, but other tests are basically normal, generally there is no need for treatment or medication, ensure sufficient rest and quit drinking, regular work and rest, reasonable diet, usually about 1 week transaminases can be reduced. Due to chronic viral hepatitis, hepatitis, cirrhosis, moderate to severe fatty liver disease, autoimmune liver disease, hepatocellular carcinoma and other disease factors caused by aminotransferases 100U / L, can be under the guidance of a doctor to use glycyrrhizin, bisabolol, polyenylphosphatidylcholine, reduced glutathione and other drugs for the corresponding treatment, the enzyme down time is slightly longer, 2-4 weeks or so. At the same time, active treatment of the primary disease is also an important factor in determining the prognosis. Patients with severe symptoms may have unsatisfactory enzyme-lowering effects and require a longer period of time. If there is any abnormal transaminase test, you should go to the hospital as soon as possible, and the doctor will formulate an individualized treatment plan according to your specific condition, so as not to delay your condition.