Which is better, Zuo Gui Wan or Zhi Bai Di Huang Wan, is related to the patient’s own specific symptoms, for those with simple kidney yin deficiency, it is more suitable to take Zuo Gui Wan; and for those with yin deficiency and fire (deficiency of yin and essence in the body, with hyperactive fire), it is more suitable to take Zhi Bai Di Huang Wan. 1. Zuo Gui Pill: Containing Chinese medicines such as Radix Rehmanniae Praeparata, Radix Achyranthis Bidentatae, Radix et Rhizoma Gastrodiae, Radix Angelicae Corii Asini, Semen Cuscutae, Fructus Lycii, Rhizoma Dioscoreae and other Chinese medicinal herbs, it has the effect of nourishing the kidney and replenishing yin, and it can be used for treating the lumbar soreness and knee weakness due to the insufficiency of genuine yin, mental fatigue, dryness of the mouth and night sweating, which can be caused by the abnormal sweating after going to bed and the stopping of sweating when waking up, but it is contraindicated in pregnant women and children, and is also not suitable for patients who suffer from colds. 2. Zhi Bai Di Huang Wan: Containing Zhi Mu, Huang Bai, Shu Di Huang, Mudan Pi, Poria, Zedo and other traditional Chinese medicines, it has the efficacy of nourishing yin and lowering fire (nourishing the yin essence and lowering the fire), and can be used for the treatment of tidal fever and night sweating caused by yin deficiency and fire (i.e., fever is sometimes like tidal wave; and night sweating at night when you go to sleep, and sweating stops when you wake up), dry mouth and throat, tinnitus, and seminal emission, etc. It is not recommended for pregnant women and children, and should not be taken by patients with colds. Pregnant women should take it with caution. The composition, efficacy and treatment of the above two drugs have certain differences, taking the contraindications and adverse reactions are not clear, the specific selection should also be based on the patient’s own specific symptoms under the guidance of a physician, not blindly self-medication.