Patients with chronic nephritis or chronic kidney disease, often combined with hypertension, which is mainly due to the following reasons: First, the kidneys secrete a lot of biologically active factors affecting blood pressure in order to regulate the blood volume of a person, when there is chronic nephritis or renal disease, the kidneys will secrete inflammatory factors, which cause the activation of the renin-angiotensin aldosterone system, which causes vasoconstriction, leading to water-sodium retention, and makes the blood pressure rise; Second, patients with chronic nephritis or chronic renal disease will suffer from sclerosis of the small renal arteries and increase in the resistance of renal blood vessels, which will cause the rise of the blood pressure; Third, due to the metamorphosis of the patients with chronic nephritis, they will reflexively cause the spasm of small renal arteries, which will cause the rise of the blood pressure.