Nosintrol is generically known as sacubitril valsartan sodium tablets and is taken to reverse apical septal thinning. Sacubitril valsartan sodium tablets are a combination of sacubitril and valsartan sodium. It can effectively block angiotensin di-receptor water-sodium retention and remodeling, and secondly, it can also inhibit vasoconstriction and aldosterone release. It is mainly used in the treatment of chronic heart failure with reduced ejection fraction and is therefore able to reverse apical septal thinning. The drug may cause discomfort with angioedema and increased serum creatinine after administration. It is contraindicated in hypersensitivity to the components of the drug, in idiopathic angioedema, in biliary cirrhosis. In the course of taking the drug, it is necessary to pay attention to angioedema, hypotension, impairment of liver and kidney functions. And pregnant and lactating women need to use the drug under medical supervision. If you need to choose Sacubitril valsartan sodium tablets for the treatment of apical septal thinning, it is recommended to take the medicine under the guidance of a doctor.