Influenza and neocoronavirus pneumonia are different in terms of causative pathogens, modes of transmission, and clinical manifestations. 1. Pathogenic pathogen: influenza is caused by influenza A, B and C viruses; the new coronavirus is the new coronavirus 2019. 2. Mode of transmission: Influenza is mainly transmitted by droplets such as sneezing and coughing; the transmission route of new coronavirus includes direct transmission, aerosol transmission and contact transmission. 3. Clinical manifestations: Influenza patients mainly manifest high fever, fatigue, generalized pain and other systemic toxic symptoms, while nasal congestion, runny nose and other respiratory symptoms are mild; new coronary pneumonia patients with fever, fatigue, dry cough as the main manifestations of the rapid progress of the disease, about 1 week can be severe hypoxemia, sepsis, coagulation disorders, and so on. It is recommended that patients with related symptoms should seek prompt medical attention for a definitive diagnosis.