Taking ibuprofen for muscle strain has some analgesic and anti-inflammatory effects. Muscle strain will appear after the break of muscle fibers, capillary rupture and other pathological changes, resulting in increased exudation of inflammatory mediators such as cyclooxygenase, leukotrienes, prostaglandins and other inflammatory mediators, and the symptoms of swelling and pain. Ibuprofen belongs to the non-steroidal anti-inflammatory drugs, can be inhibited through the inhibition of cyclo-oxygenase, reduce the synthesis of prostaglandins, and play a role in relieving pain, inhibiting the effect of inflammatory response. The more common adverse reactions to ibuprofen are gastrointestinal reactions, such as dyspepsia, bloating, nausea, vomiting, etc., and in severe cases can lead to gastric ulcers and gastrointestinal hemorrhage; bone marrow suppression and hepatic impairment can also be seen in high doses. Patients with gastrointestinal bleeding or perforation, those with severe hepatic or renal insufficiency, or those with severe heart failure. Ibuprofen is contraindicated in people who are allergic to ibuprofen, pregnant and lactating women. Ibuprofen needs to be used under medical supervision to avoid self-medication and adverse reactions.