In recent years, the number of liver diseases caused by improper medication has been increasing year by year. Many people are sick without first consulting a physician to guide the use of drugs, and take them as directed, most likely to cause liver damage. There are hundreds of drugs that can cause different degrees of liver damage, including our common sedative and sleeping drugs (such as chlorpromazine, Valium, etc.), certain antibiotics (such as sulfonamides, rifampin, tetracycline, erythromycin), anti-cold drugs, anti-cancer drugs, antipyretic and analgesic drugs, hypoglycemic drugs, anti-rheumatic drugs, and certain Chinese medicines. Drug-related hepatitis is mainly manifested as liver discomfort, bloating, loss of appetite, nausea, weakness, yellow urine and even jaundice, similar to acute viral hepatitis, a few hours to a few days after taking the drug. Drug-related hepatitis is ultimately caused by the use of drugs, and prevention is important. Before taking any medication (including Chinese, herbal and tonic medicines), ask your doctor if there is any possibility of hepatotoxicity from the drug. Do not assume that herbs, medicines and supplements are “mild” and will not be hepatotoxic. As the saying goes, “medicine is poisonous in three parts”, as long as it is a medicine, it may produce hepatotoxicity. Many prescriptions that claim to be “liver-protective” or “liver-strengthening” are, in fact, hepatotoxic. It is a good idea to keep track of your medication to help your physician determine if your liver disease is related to the medication. When taking a drug for a long period of time, regular blood, urine and liver and kidney function tests should be performed. Once symptoms appear, stop the medication and seek medical attention in time to avoid more serious liver damage. With good medication habits, it is possible to reduce or avoid damage to the liver from drugs.