Prolonged use of insulin pumps may cause hypoglycemia, hyperglycemia, infusion site reactions, infections, and other adverse conditions, but not in all wearers. Insulin pump is a device used for the treatment of diabetes mellitus, which can accurately infuse insulin under the skin of patients according to the body’s insulin demand, and can also mimic the characteristics of the human body’s insulin secretion. The use of insulin pumps may cause hypoglycemia if the parameter settings are not in accordance with the doctor’s instructions, improper implantation site, untimely or insufficient food intake, etc. Hyperglycemia can also be caused by insufficient power of the pump, exhaustion of insulin in the drug reservoir, improper placement of needles, etc. The prolonged use of insulin pumps can cause redness at the infusion site, itching of the skin and other conditions. In addition, the insulin pump will set the catheter under the skin, and the place where the catheter enters after long-term use of the insulin pump is very easy to induce infection. Patients who need to use insulin pump treatment should actively cooperate with the doctor’s treatment, and if any uncomfortable symptoms appear after using insulin pump, it is recommended to go to the hospital for consultation.