The causes of schizophrenia include the following: 1, the onset of schizophrenia is first related to genetics, but genetics is relative, not absolute genetics, that is, two lines of three generations of family members with a family history of schizophrenia disease, the proportion of his children with schizophrenia is significantly higher than the normal population; 2, personality factors, many schizophrenic patients are relatively introverted personality, more sensitive and suspicious, timid and fearful, not good at human interaction. Patients with this type of personality trait are not good at expressing themselves and may have thinking and emotional disorders, which is also a cause of the disease; 3, the impact of family and social environment factors, such as improper family upbringing, lack of care, more family conflicts, and social reasons such as high social pressure and academic pressure, which may lead to the onset of the patient The onset of the disease may occur; 4. It is related to the structural abnormalities of the patient’s brain. Some new studies have found that patients with minor brain damage during the perinatal period or the birth of a child have an increased rate of schizophrenia in adolescence; 5. Biochemical factors, patients with a recent onset may have a relationship with abnormalities in the pituitary, thalamus, adrenaline axis, or thyroxin axis. There are also biochemical factors, i.e., the onset of schizophrenia may be related to the secretion of dopamine, and dopamine hypersecretion is also a major cause of schizophrenia onset.