If you still can’t open your mouth after a week of wisdom teeth extraction, you may need anti-inflammatory treatment, physical therapy, mouth opening training, etc. We suggest you to go to the hospital for specific examination and treatment. 1. One week after wisdom teeth extraction and still can not open the mouth may be caused by infection, this can be systemic anti-inflammatory treatment and local anti-inflammatory treatment. 2. Systemic anti-inflammatory can be oral or intravenous antibiotics, commonly used penicillin or erythromycin and other drugs. Locally, you can clean up the extraction wound, rinse out the pus, and then apply iodized glycerin and other drugs to locally reduce the inflammation. 3. If the temporomandibular joint ligaments have problems due to the long time without opening the mouth, you may need ultrashort wave physiotherapy, and you can also apply localized hot compresses. In addition, you also need to do mouth training, do not force to expand the degree of mouth opening, you can try to increase the degree of mouth opening little by little, it is recommended to go to the hospital for examination and treatment, the use of drugs need to follow the doctor’s instructions.