Most of the drugs used to lower urine protein are of the ACEI or ARB class. Glucocorticoids are effective in fighting infection and reducing urinary protein. In addition, glucocorticosteroids have other effects, but when taking glucocorticosteroids patients may experience some side effects, such as centripetal obesity, full-moon face, and low immunity and infection after long-term use of glucocorticosteroids. Overall, the benefits of glucocorticosteroids outweigh the drawbacks, which is exactly why glucocorticosteroids are still appearing in clinical practice. Specific drugs to reduce urinary protein should be determined according to the actual condition of the patient.