Many people think that lack of appetite, not being able to eat and weight loss are signs of anorexia, so they do not pay much attention to them. However, I would like to tell you today that this kind of appetite, not eating and weight loss may also be caused by another disease – bile duct cancer. What is bile duct cancer? Bile duct cancer usually refers to cancer of the major hepatic ducts and extrahepatic bile ducts. Why does cholangiocarcinoma occur? The occurrence of bile duct cancer may be related to chronic inflammation of the bile duct, such as: primary sclerosing cholangitis, bile duct stones, biliary parasitic disease, hepatitis C, chronic ulcerative colitis, etc. may increase the chance of bile duct cancer. In addition, the occurrence of bile duct cancer is also related to diet. People who often eat high oil and high calorie food, or often smoke or drink alcohol, or have “three highs” or metabolic syndrome, are prone to bile duct cancer.