Intrahepatic space-occupying lesions indicate the presence of a nodule in the liver and require further examination to determine the nature of the nodule; they are categorized into benign space-occupying diseases and malignant space-occupying diseases. 1. Benign space-occupying diseases: most of the liver space-occupying lesions found in physical examination are benign liver space, liver cysts and liver hemangiomas are the most common, but there may also be focal nodular hyperplasia, liver adenoma, and so on. 2. Malignant space-occupying disease: primary hepatocellular carcinoma and metastatic hepatocellular carcinoma are malignant space-occupying diseases; ultrasound examination of hepatitis B patients shows that there is space-occupying disease, and liver enhancement CT and magnetic resonance examination are needed. Measurement of alpha-fetoprotein and hepatitis virus screening are also performed. Patients who find occupying lesions in the liver are recommended to go to the hospital as soon as possible and receive targeted treatment under the guidance of physicians to avoid further aggravation of the condition.