Commonly used clinical antipyretic drugs mainly include acetaminophen, anandamide, ibuprofen, lysine for injection, etc. These drugs can bring down the body temperature quickly. Chinese patent medicines such as pediatric black bean and fever clearing granules and Xinxue granules are also very effective in reducing fever with little side effects and do not reduce granulocytes. Dexamethasone can also be used to reduce fever when necessary to avoid damage to target organs, but it cannot be used routinely because of its side effects. Ibuprofen and Pediatric Soybean Fever Granules can be used to reduce fever in infants and children and relieve the discomfort caused by various infections, while acetaminophen has a rapid and reliable antipyretic effect and can be preferred for adults. Lysergic acid has a strong antipyretic effect, with a rapid onset of action and a moderate and long-lasting effect, avoiding the irritation of the gastrointestinal tract caused by oral aspirin and ibuprofen. Fever is a defensive reaction, but high fever can cause complications and requires antipyretic treatment, but the dosage should not be too high to avoid excessive sweating causing deficiency, especially for infants and young children, the elderly and frail.