Sensitive skin with acne and closed mouth can be treated with general treatment, medication, and acne removal. Pimples and closed mouth are all part of the clinical manifestations of acne. 1. General treatment: patients should do a good job of daily skin cleansing, choose the right cleaning products, to avoid over-cleaning leading to aggravation of symptoms. Daily diet should be light, and avoid scratching with hands to avoid infection. 2. medication: patients can follow the doctor’s instructions for external use of adapalene gel, retinoic acid cream, peroxybenzoyl gel, etc. to improve acne occlusion. If the patient urgently needs to improve the symptoms of occlusion, you can follow the doctor’s instructions to take oral retinoids. Sensitive skin patients are recommended to strictly follow the doctor’s instructions to avoid adverse drug reactions. 3. Acne removal: acne can be squeezed out using an acne squeezer under adequate sterilization. If the symptoms of acne on sensitive skin are more serious, it is recommended that the patient go to the hospital in time, follow the doctor’s instructions to use the above medication, do not use drugs indiscriminately, so as not to lead to adverse consequences.