Treatment is mainly aimed at correcting the pathophysiological process (e.g., sodium and water retention, blood volume overload) through symptomatic treatment, preventing acute complications, and protecting renal function to facilitate natural recovery. Rest Regardless of the severity of the disease, bed rest should be provided in the early stage until the edema subsides significantly, the blood pressure becomes normal and the hematuria disappears, which usually takes 2 to 3 weeks. After the blood sedimentation is normalized, you can go to school, but you should control the activity level. Diet During the acute phase, it is advisable to limit the intake of water, salt and protein. A low salt or salt-free, low protein diet is usually used, with sugar to provide calories. Salt intake should be controlled at the level of 1~2g/d. In case of renal insufficiency, a high quality protein intake of 0.5g/(kg-d) is appropriate. Diet can be given low protein, low salt, low potassium and low phosphorus food, and should be mainly high quality protein, such as eggs, meat and milk protein. Water restriction is recommended for those with heavy edema and low urine output. Treatment of infected foci Penicillin injection for 10-14 days at the beginning of the disease was previously advocated, but its necessity is controversial. However, if the lesion is positive for bacterial culture, antibiotic treatment should be given aggressively. For chronic tonsillitis with recurrent attacks, tonsil removal should be considered after the condition is stabilized, and penicillin injection should be given for 1-2 weeks before and after the operation. Diuretic application The main pathophysiological changes in acute nephritis are sodium and water retention and expansion of extracellular fluid, so the application of diuretics not only achieves diuretic and swelling effects, but also helps prevent and control complications. Diuretics should be given to anyone with low urine, edema and high blood pressure despite water and salt control. For mild edema, hydrochlorothiazide 2-3mg/(kg-d) can be used orally, and spironolactone 2mg/(kg-d) can be added after the urine volume increases. Patients with poor oral diuretic effect or severe edema can take intravenous drip or intramuscular injection of furosemide 1~2mg/kg each time. new diuretic combination of dopamine and phentolamine 0.3~0.5mg/kg each and furosemide 2mg/kg together with 10% glucose 100~200ml IV, the diuretic effect is better than furosemide alone. Application of antihypertensive drugs Anyone whose blood pressure is still high after rest, water and salt restriction and diuresis should be given antihypertensive drugs. The first choice is nifedipine (nifedipine), 0.25-0.5mg/kg per dose, 3-4 times/d orally or sublingually. If blood pressure is still not controlled, use nicardipine 0.5-1mg/kg per dose, 2 times/d; Captopril (Captopril) 1-2mg/(kg-d), 2-3 times/d.