With the accelerated pace of social life, men today are under more and more pressure of social and family life, especially middle-aged men over 45 years old, as the backbone of the family, bearing the responsibility of “the old and the young”, coupled with environmental pollution and bad habits such as long-term late night, smoking and drinking, their Their health condition is worrying. The men in this age group have little awareness of self-examination and are unaware that certain diseases, especially male diseases, may have crept up on them, but they are unaware of it. So, how can certain diseases, especially male diseases, be detected early? The best option is to have a regular annual checkup, but only if you go to a medical institution that is qualified to do so. The body of middle-aged men over 45 years of age is starting to go downhill, the physical examination at this time is particularly important, but also the best way to evaluate the physiological condition of the body, so what physical examination items should be done? And what is the significance of it? First of all, routine liver and kidney function, lipid, blood sugar, uric acid and other tests are needed to help determine whether there is a metabolic syndrome or a tendency to do so, such as diabetes, high blood lipid and high uric acid, so as to guide the daily diet and lifestyle habits. Next, a sex hormone test is needed to see if there is late-onset hypogonadism, also known as middle-aged male menopause. This is because late-onset hypogonadism is characterized by hot flashes, excessive sweating, palpitations, insomnia and anxiety, as well as hypogonadism such as impotence and premature ejaculation, which affects family life and the relationship between husband and wife. Some men are reluctant to take the initiative to go to the hospital for examination because it is difficult to talk about it, through the routine physical examination, it is easy to accept, and at the same time find the problem can be diagnosed and treated early. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The actual fact is that it is necessary for middle-aged men over 45 years old to have regular annual checkups to determine the condition of their bodies, and based on the checkup report, doctors can formulate a scientific and reasonable diet and work schedule, so that even if certain diseases are found, they can be diagnosed and treated early to protect your health.