Gastrointestinal sinus enterosis is intestinal epithelial hyperplasia, which is usually considered to be treated with medication first, and then surgery after medication fails. Gastric sinus enterosis does not necessarily require surgical treatment. Gastric sinusitis is a kind of gastric mucosal tissue damage after the intestinal epithelial growth performance, belongs to a kind of gastritis is more common symptoms, can be considered to accept conservative treatment, such as taking gastric mucosal protective agent magnesium carbonate chewable tablets; proton pump inhibitors, such as omeprazole and lansoprazole, and so on. If the patient receives conservative treatment after the intestinalization has not been reversed, towards atypical hyperplasia or cancerous transformation, at this time you can consider undergoing surgical treatment, mainly in the endoscopic help to peel off the intestinalized tissues, but also in the endoscopic cauterization treatment, and need to be regularly re-examined. Gastric sinus enterocytosis has a certain degree of danger, if there is discomfort, timely medical treatment, patients need to follow the doctor’s instructions to actively accept the treatment.