Transaminase 168U/L is a moderate liver function abnormality, which is not very serious. Elevated transaminases should be identified as physiologic or pathologic causes, and it is recommended that patients should seek timely medical attention to identify the specific causes and follow the doctor’s instructions for treatment. 1. Physiological causes: unhealthy dietary habits, such as alcoholism, heavy drinking and overeating, can easily lead to a temporary increase in transaminases. 2. Pathological causes: viral hepatitis, alcoholic liver disease, drug liver injury, autoimmune liver disease and metabolic liver disease can cause transaminase increase. Autoimmune diseases can also damage the liver, resulting in hepatocellular necrosis and increased transaminases. If patients have unexplained transaminase elevation, it is recommended to go to the hospital in time for detailed diagnosis and treatment to find out the cause of the disease and avoid delaying the condition.