There is no specific antidote for succinylcholine. Succinylcholine is a depolarizing skeletal muscle relaxant that is not readily absorbed orally, and its muscarinic effect occurs within one minute of sedation, and it is generally used for tracheal intubation during general anesthesia and for maintaining muscarinic effect during surgery.
Succinylcholine has no antagonist, anticholinesterase drugs such as neostigmine not only can not antagonize, but also increase its muscarinic effect.
Non-depolarizing and depolarizing muscarinic drugs may antagonize each other. In adults, the first injection of 3-5mg of cylinder arrow toxin can relieve the muscle fascicular tremor of succinylcholine.
If the patient develops symptoms such as respiratory paralysis, prompt symptomatic treatment with respiratory support such as ventilator and artificial respiration is recommended and should be performed under medical supervision. In the event of prolonged respiratory arrest, artificial respiration must be used, as well as blood transfusion, injection of dried plasma or other cholinesterase mimetics, but not neostigmine.
In addition, you can also promote the metabolism of drugs in the body by applying diuretic drugs such as furosemide, in addition to the clinic is often infused with sodium chloride, glucose solution to accelerate the metabolism of drugs, to maintain the body’s water-electrolyte balance. This can be done under the guidance of a doctor.
If such a situation as the above occurs, it should be timely to seek medical attention.