Boils can grow between the vagina and anus. Boils are inflammatory reactions caused by bacterial infection of individual hair follicles and their surrounding interstitial tissues, etc. They are most common on the face, neck, and buttocks where sebaceous glands are abundantly distributed. As sebaceous glands can secrete lipids, sweat and other secretions through hair follicles, if the follicles are blocked, the secretions stagnate in the follicles to form a natural medium, bacteria such as Staphylococcus aureus can enter the local tissues through the follicles, damaging the cells and resulting in a localized acute suppurative inflammation, which appears to be a boil if only one hair follicle is involved. The sebaceous glands between the vagina and the anus are more widely distributed, and sweating, tight underwear and friction may cause the hair follicles to become clogged, and boils will grow when they are infected with Staphylococcus aureus. However, sebaceous cysts, warts and other swellings can also appear between the vagina and anus. It is recommended that patients go to a regular hospital as soon as possible for systematic examination, differential diagnosis, clarification of the nature of the swelling, and early treatment to avoid delays in the condition.