Most men with a burning and stinging sensation in the urethra have a urinary tract infection. If a routine urine check can indicate a significantly elevated white blood cell count or bacterial count, medication can be given at this time. Generally speaking, the commonly used drugs are levofloxacin, cephalosporins, roxithromycin, clarithromycin, etc. If the urine bacterial culture can be done, according to the results of the drug allergy, the causative bacteria can be clarified, and the drug that is sensitive to the bacteria will be more effective in treatment. If there is a combination of abnormal discharge from the urethra, it is necessary to take the discharge for bacterial culture and mycoplasma culture. If there is a mycoplasma infection, the results of the drug sensitivity can be used to give drugs such as clarithromycin and doxycycline.