Cephalosporins can be used together with levofloxacin. Cephalosporins and levofloxacin have no contraindications, and can be used together clinically, and their combined use can expand the antibacterial spectrum. However, in the anti-infective treatment, generally should try to choose a single drug, such as no special needs of the disease, usually choose a single antibiotic to use, only when a single use of an antibiotic can not achieve the therapeutic effect, only to consider the two antimicrobial drugs used together. The above two drugs need to pay attention to the adverse reactions, such as allergies, skin rashes and other conditions need to stop the drug, pay attention to the use of antibiotics when the disease is cured that need to stop, can not be abused for a long time. Specific drug use is recommended to the regular hospital after a clear diagnosis, by the doctor’s guidance, to avoid adverse consequences.