The cause of laryngeal cartilage tenderness is not well understood and occurs mostly in infants and young children. It may be due to calcium deficiency, vitamin D deficiency, thyroid cartilage, cricoid cartilage, etc. during the growth and development of infants and young children, which leads to soft laryngeal cartilage due to osteogenesis disorders in the larynx and collapse during breathing, especially during inspiration, and in severe cases, breathing difficulties or even asphyxia. It can also be caused by congenital factors that lead to softening of laryngeal cartilage, but nowadays this disease is becoming less and less common as people’s standard of living improves. Prevention of this disease should start from the mother’s pregnancy with prenatal checkups and screening for related diseases, and pregnant women should pay attention to nutrition, supplementation of trace elements, and more sunshine to promote bone resorption and bone formation. Babies should be born in the sun, pay attention to the addition of complementary foods, etc., and seek medical attention when abnormalities occur.