When a baby takes ibuprofen to reduce fever and then has a fever again, physical or medication cooling treatment is needed depending on the baby’s specific condition. At the same time for the cause of the treatment is also important for the recovery of body temperature. Fever is a common symptom in childhood. Baby fever after taking ibuprofen and then fever, if the body temperature in 38.5 ℃ or less than 4 hours from the last drug interval, can use warm water on the forehead, warm bath, reduce the wearing of clothing, antipyretic stickers, antipyretic blankets, fans and reduce the temperature of the room, and other physical ways to reduce heat treatment. If the temperature exceeds 38.5℃ and the time since the last medication is more than 4 hours, in addition to the above physical methods to reduce the temperature, it is also necessary to follow the doctor’s advice to continue to take oral ibuprofen, acetaminophen and other drugs for antipyretic treatment. For children with fever, the speed of normalization of body temperature is closely related to the state of the disease, so it is also very crucial to treat the cause. Fever caused by influenza virus can be treated with oseltamivir; fever caused by bacterial infection can be treated with cefixime, penicillin and other drugs. All of the above drugs should be used under the guidance of a doctor, avoid self-medication. There are many other causes of recurrent fever in babies, and it is recommended to consult a specialist for evaluation and treatment.