Coronal pearly papules are benign lesions, usually caused by pearly penile papules, and are strongly associated with long-term local irritation from secretions. Although it is a benign lesion, it needs to be treated promptly because it grows in the coronal sulcus and is densely packed with papules. At this stage, the main treatments for coronal pearly eruptions are medication, laser treatment and cryotherapy. Although pearly pimples do not have obvious conscious symptoms, they look scary from the symptoms, and because they grow on the penis, many men want to remove them. The traditional medication is usually a boric acid solution, potassium permanganate solution, and glycolate lotion and other drugs, washing the entire pubic area and then applying Euthyrox, acyclovir ointment, mometasone ointment and other drugs to treat the coronal pearly pimples, the effect of drugs is not very obvious. At present the more used method is to carry out laser treatment, the laser can remove the growth of pearl papules at once, and the trauma is small, the bleeding is also less, the recovery is also relatively fast. The number of coronal pearly whites that are small but large can be treated with cryotherapy, the principle of cryotherapy and laser are actually the same and the results are more satisfying. In fact, coronal pearly whites is a self-limiting disease, meaning that it grows to a certain size and will not grow again, and there is no great impact and harm to the human body, if there are no economic conditions can not be treated.