Some blood pressure medications can cause bradycardia. Common blood pressure medications that cause bradycardia include beta-blockers, such as metoprolol and bisoprolol, and nondihydropyridine calcium channel blockers, such as verapamil and diltiazem. beta-blockers cause slowing of the heartbeat by inhibiting the heart’s beta1-adrenergic receptor. Non-dihydropyridine calcium channel blockers also cause bradycardia because of their inhibitory effect on the function of the sinus node and atrioventricular node. When using these two antihypertensive drugs, you need to pay attention to the patient’s heart rate, and if severe bradycardia occurs, you need to adjust the dose of antihypertensive drugs. For patients who have bradycardia, avoid using these two antihypertensive drugs.