Patients with leukemia sometimes have very severe pain in their body, which is more severe. 1. After suffering from leukemia, leukemia cells in the medullary cavity proliferate excessively, infiltrate the bone and periosteum, and stimulate the sensory nerves, thus causing pain. The pain often occurs in the bones and joints, the pain in the back and limb area is more obvious, diffuse pain is dominant and widespread, and some patients may feel pain all over the body. The pain is more intense, and some patients may even have difficulty moving. 2. In addition, leukemia patients have the risk of complications of bone marrow necrosis, with bone joint pain and fever as the main manifestations, bone pain will usually be acute attacks, often located in the lower back, the pain is intense. Leukemia patients should receive active and standardized treatment under the guidance of physicians, and only when the disease is under control can the pain symptoms be relieved.