During the use of nifurtimox, mild itching may occur, which is a normal reaction, while more severe itching is abnormal, which may be caused by drug allergy. Nifurtimox is mainly used for the treatment of trichomoniasis, mycosis vaginalis, bacterial vaginosis or cervicitis and other gynecological inflammatory diseases caused by abnormal vaginal discharge, yellowish leukorrhea, itching, odor and other symptoms. Under normal circumstances, after the use of the drug due to the therapeutic effect of drugs, women’s vaginal abnormal leukorrhea and itching symptoms will be reduced; if after the use of the drug after the itching symptoms do not see relief but further aggravation, or accompanied by obvious burning sensation in the vagina, it is most often considered to be the drug allergy caused by the need to stop using the drug.