Hydroquinone cream is used for the treatment of chloasma, freckles and hyperpigmentation as a skin discoloring agent that produces reversible skin discoloration by inhibiting the metabolic processes of melanocytes. The medication can be irritating to the skin and individuals may experience allergic side effects. Before using the drug on its sensitivity to skin test, can be applied to the undamaged skin for 24 hours, if a small amount of erythema, it is not necessary to disable the drug. However, if burning sensation, itching, blisters or specific inflammatory reaction occurs at the site of application, it is recommended to discontinue the use of the drug. Avoid sunlight at the site of application. Note that this product should only be used on the lesion area, do not apply to normal skin. It is contraindicated for those who are allergic to the product, children under 12 years of age and pregnant women. The use of hydroquinone cream must follow the doctor’s instructions, do not blindly treat yourself to avoid adverse reactions.