Chemotherapy may produce side effects, such as numbness in the hands and feet, which may be caused by the peripheral nerve reaction to chemotherapy drugs. Generally speaking, it can be recovered, but in some cases, it is more difficult to recover from severe numbness of hands and feet, and it is necessary to apply rehabilitation physiotherapy and nerve-nourishing drugs. For example, among chemotherapy drugs, oxaliplatin causes numbness in the hands and feet, which can be improved by avoiding cold and reducing the dosage of drugs. If the symptoms of numbness in the hands and feet are more severe, you can consider applying nerve-nourishing drugs. In addition, chemotherapy may cause nausea, vomiting, poor appetite and other gastrointestinal reactions in addition to numbness in the hands and feet, and may also cause a decrease in white blood cells, hemoglobin, anemia and other bone marrow suppression reactions.