Coronary artery disease caused by pulmonary effusion should be given diuretic, vasodilator drug therapy, such as furosemide, isosorbide nitrate and so on as prescribed by the doctor. For the combination of hypoproteinemia patients to supplement protein, while actively treating coronary heart disease. Coronary artery disease patients occur pulmonary effusion is mostly seen in patients with heart failure, severe myocardial ischemia will lead to decreased myocardial contractility, pulmonary effusion. Diuretics, such as furosemide and spironolactone, can be given to patients, and oral vasodilator drugs, such as isosorbide nitrate, are also needed. Some patients may be combined with hypoproteinemia, which can be supplemented with intravenous albumin to increase the effect of diuresis. Patients with coronary artery disease should be given aspirin atorvastatin and other medications to prevent the progression of atherosclerosis and reduce the symptoms of heart failure caused by myocardial ischemia, and patients with lung infections need to be given anti-infective medications at the same time. Coronary artery disease caused by pulmonary effusion, to the hospital in a timely manner, under the guidance of the physician can be treated.