In recent years, the number of patients with nephritis and acute renal failure due to indiscriminate use of herbal medicines is increasing. The experts call for this: the need to raise awareness of the nephrotoxicity of herbs. According to experts, for many years, the claim that “Chinese medicine has few side effects” has made people lack sufficient awareness and attention to the nephrotoxicity of certain herbs. In the mid-1990s, Belgian doctors first discovered that a considerable number of “fat girls” and “fat sisters-in-law” suffered from acute kidney failure after taking weight-loss herbs without any taboos, thus introducing the concept of “Chinese medicine nephropathy”. Studies have shown that the aristolochic acid contained in the Chinese medicines Moutong, Houpao, Fantao and Hesperidin can lead to renal tubular and interstitial, proximal tubular acidosis and hypotonic urine. Such patients present with oliguric acute renal failure at the beginning of the clinical period, which turns into chronic tubulointerstitial nephritis over time. And these patients are extremely difficult to treat, often gradually towards end-stage failure. Experts emphasize that many charlatans, under the banner of “partial prescriptions” and “experimental prescriptions”, abuse herbal medicines to treat various kidney diseases, aggravating the condition of patients and even leading to uremia, which must be vigilant. Studies have found that nearly 50 kinds of Chinese medicines are toxic to the kidneys and can cause acute and chronic renal impairment and kidney failure. There are three types of herbal medicines that can cause kidney damage: the first one is plant-based herbal medicines: Leigongteng, Cao Wu, Moutong, Jun Zi, Yi Mao Cao, Cang Er Zi, Bitter Cambodian Peel, Smallpox Powder, Petunia, Jin Zhen Zhen Root, Tu Bei Mu, Ma Er Zhong, Tu Jing Wu, Ba Dou, Aloe Vera, Iron Foot Wailing Fairy, Da Feng Zi, Shan Ci Mushroom, Mandarins, Di Di Di Feng, Zigong Leaves, Ze Xie Di, Fang Shi, Gan Sui, Qian Li Guang, Ding Xiang, Ming Veng, Bupleurum, Bupleurum, Dwarf ground tea, bitter ginseng, hyssop, Wangnanzi, cotton seeds, waxberry root, etc. The second category is animal herbal medicine: fish gall bladder, seahorse, centipede, snake venom, etc. The third category is mineral herbal medicines: arsenic-containing (arsenic, arsenicum, xionghuang, red alum), mercury-containing (cinnabar, mercury, light powder), lead-containing (lead pellets) and other minerals (alum), etc.