Elevated B-type brain natriuretic peptide is often indicative of heart failure, but studies have found that elevated B-type brain natriuretic peptide is also seen in patients with acute cerebral infarction, renal insufficiency, etc. B-type brain natriuretic peptide is mainly synthesized and secreted by ventricular myocytes, and when ventricular wall tension changes and ventricular load increases, the synthesis and secretion of B-type brain natriuretic peptide by ventricular myocytes increases, thus exerting a pro-urinary and pro-sodium effect and promoting vasodilation, which can reduce the normal physiological activity of the heart to a certain extent. B-type brain natriuretic peptide is a common index in the diagnosis and treatment of heart failure, and B-type brain natriuretic peptide precursors are more specific for the diagnosis of heart failure, which can be caused by a variety of diseases and needs to be combined with symptoms and other clinical examination results for a comprehensive judgment.