Stage 3 colon cancer has a certain degree of impact on the life expectancy of patients, which needs to be considered according to the patient’s pathological type, physical condition and selected treatment means. Clinically, “5-year survival rate” is commonly used to roughly assess the survival of tumor patients, which refers to the proportion of patients who survive for more than 5 years after comprehensive treatment. According to GLOBOCAN data, the 5-year survival rate of stage I colon cancer is about 95%, stage II is about 90%, stage III is about 70%, and stage IV is only about 15%. Stage III colon cancer often has lymph node metastasis or deep infiltration of local lesions, which is not an early stage lesion. After diagnosis, it needs to be actively treated, and appropriate treatment modalities should be selected according to the actual situation of patients in order to prolong the overall survival time. It should be noted that colon cancer can improve the prognosis through “early detection, early diagnosis and early treatment”, and it is recommended that people with high risk factors for colon cancer should complete colonoscopy in time.